{"@context":"https://schema.org","@graph":[{"@id":"https://thehippiescientist.net/herbs/boldo/#entity","@type":["Substance","Thing"],"additionalProperty":[{"@type":"PropertyValue","propertyID":"evidence tier","value":"Limited evidence"},{"@type":"PropertyValue","propertyID":"evidence label","value":"C"},{"@type":"PropertyValue","propertyID":"AI entity completeness score","value":40}],"alternateName":["Peumus boldus"],"description":"Boldo (Peumus boldus) carries a Grade C rating — limited evidence. Strongest recorded design is a narrative review, drawn from 1 recorded study, none of which measured an outcome in people. Recorded activity centres on digestive support and hepatobiliary support, which describes mechanism rather than demonstrated benefit. Noted cautions include pregnancy or breastfeeding without clinician guidance.","identifier":[{"@type":"PropertyValue","propertyID":"THS entity id","value":"ths:herb:boldo"},{"@type":"PropertyValue","propertyID":"THS slug","value":"boldo"}],"name":"Boldo","subjectOf":{"@id":"https://thehippiescientist.net/herbs/boldo/#evidence-data"},"url":"https://thehippiescientist.net/herbs/boldo/"},{"@id":"https://thehippiescientist.net/herbs/boldo/#evidence-data","@type":"Article","about":{"@id":"https://thehippiescientist.net/herbs/boldo/#entity"},"author":{"@type":"Person","name":"Willie B. Randolph III","url":"https://thehippiescientist.net/info/author/","@id":"https://thehippiescientist.net/info/author/#person","affiliation":{"@id":"https://thehippiescientist.net/#organization"}},"citation":[{"@id":"https://doi.org/10.1691/ph.2021.1684"},{"@id":"https://doi.org/10.1186/s40659-025-00647-w"},{"@id":"https://doi.org/10.3390/ijms26094326"}],"description":"Boldo (Peumus boldus) carries a Grade C rating — limited evidence. Strongest recorded design is a narrative review, drawn from 1 recorded study, none of which measured an outcome in people. Recorded activity centres on digestive support and hepatobiliary support, which describes mechanism rather than demonstrated benefit. Noted cautions include pregnancy or breastfeeding without clinician guidance.","headline":"Boldo evidence, safety, and entity data","mainEntity":{"@id":"https://thehippiescientist.net/herbs/boldo/#entity"},"publisher":{"@type":"Organization","name":"The Hippie Scientist","url":"https://thehippiescientist.net","@id":"https://thehippiescientist.net/#organization"},"url":"https://thehippiescientist.net/herbs/boldo/"},{"@id":"https://doi.org/10.1691/ph.2021.1684","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/boldo/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"narrative review"}],"author":{"@type":"Organization","name":"Abushammala I et al."},"datePublished":"2021","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.1691/ph.2021.1684"},{"@type":"PropertyValue","propertyID":"PMID","value":"34620272"}],"name":"Tacrolimus and herbs interactions: a review","publisher":{"@type":"Organization","name":"Pharmazie"},"url":"https://pubmed.ncbi.nlm.nih.gov/34620272/"},{"@id":"https://doi.org/10.1186/s40659-025-00647-w","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/boldo/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"other"}],"author":{"@type":"Organization","name":"García-Rodríguez C et al."},"datePublished":"2025","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.1186/s40659-025-00647-w"},{"@type":"PropertyValue","propertyID":"PMID","value":"41353162"}],"name":"Boldo leaves reduce seizures, neuroinflammation, and hemichannel activity in a murine model of chronic epilepsy","publisher":{"@type":"Organization","name":"Biol Res"},"url":"https://pubmed.ncbi.nlm.nih.gov/41353162/"},{"@id":"https://doi.org/10.3390/ijms26094326","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/boldo/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"other"}],"author":{"@type":"Organization","name":"Montaldo L et al."},"datePublished":"2025","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.3390/ijms26094326"},{"@type":"PropertyValue","propertyID":"PMID","value":"40362563"}],"name":"Peumus boldus Extract Inhibits Lipid Accumulation in 3T3-L1 Adipocytes","publisher":{"@type":"Organization","name":"Int J Mol Sci"},"url":"https://pubmed.ncbi.nlm.nih.gov/40362563/"}]}
