{"@context":"https://schema.org","@graph":[{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity","@type":["Substance","Thing"],"additionalProperty":[{"@type":"PropertyValue","propertyID":"evidence tier","value":"Limited evidence"},{"@type":"PropertyValue","propertyID":"evidence label","value":"C"},{"@type":"PropertyValue","propertyID":"AI entity completeness score","value":40}],"description":"Nelumbo Nucifera (Nelumbo nucifera) carries a Grade C rating — limited evidence. Strongest recorded design is a randomized controlled trial, drawn from 3 recorded studies, 1 in people. Recorded activity centres on metabolic regulation, stress response modulation and AMPK signaling, which describes mechanism rather than demonstrated benefit. Noted cautions include pregnancy/breastfeeding without clinician supervision and known allergy to the plant/family.","identifier":[{"@type":"PropertyValue","propertyID":"THS entity id","value":"ths:herb:nelumbo-nucifera"},{"@type":"PropertyValue","propertyID":"THS slug","value":"nelumbo-nucifera"}],"name":"Nelumbo Nucifera","subjectOf":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#evidence-data"},"url":"https://thehippiescientist.net/herbs/nelumbo-nucifera/"},{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#evidence-data","@type":"Article","about":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity"},"author":{"@type":"Person","name":"Willie B. Randolph III","url":"https://thehippiescientist.net/info/author/","@id":"https://thehippiescientist.net/info/author/#person","affiliation":{"@id":"https://thehippiescientist.net/#organization"}},"citation":[{"@id":"https://doi.org/10.1155/2015/709628"},{"@id":"https://doi.org/10.1021/acs.jafc.4c04929"},{"@id":"https://doi.org/10.3390/ijms22158237"}],"description":"Nelumbo Nucifera (Nelumbo nucifera) carries a Grade C rating — limited evidence. Strongest recorded design is a randomized controlled trial, drawn from 3 recorded studies, 1 in people. Recorded activity centres on metabolic regulation, stress response modulation and AMPK signaling, which describes mechanism rather than demonstrated benefit. Noted cautions include pregnancy/breastfeeding without clinician supervision and known allergy to the plant/family.","headline":"Nelumbo Nucifera evidence, safety, and entity data","mainEntity":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity"},"publisher":{"@type":"Organization","name":"The Hippie Scientist","url":"https://thehippiescientist.net","@id":"https://thehippiescientist.net/#organization"},"url":"https://thehippiescientist.net/herbs/nelumbo-nucifera/"},{"@id":"https://doi.org/10.1155/2015/709628","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"narrative review"}],"author":{"@type":"Organization","name":"Jadoon S et al."},"datePublished":"2015","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.1155/2015/709628"},{"@type":"PropertyValue","propertyID":"PMID","value":"26448818"}],"name":"Anti-Aging Potential of Phytoextract Loaded-Pharmaceutical Creams for Human Skin Cell Longetivity","publisher":{"@type":"Organization","name":"Oxid Med Cell Longev"},"url":"https://pubmed.ncbi.nlm.nih.gov/26448818/"},{"@id":"https://doi.org/10.1021/acs.jafc.4c04929","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"other"}],"author":{"@type":"Organization","name":"Qiu J et al."},"datePublished":"2024","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.1021/acs.jafc.4c04929"},{"@type":"PropertyValue","propertyID":"PMID","value":"39445611"}],"name":"Nuciferine Alleviates High-Fat Diet- and ApoE(-/-)-Induced Hepatic Steatosis and Ferroptosis in NAFLD Mice via the PPARα Signaling Pathway","publisher":{"@type":"Organization","name":"J Agric Food Chem"},"url":"https://pubmed.ncbi.nlm.nih.gov/39445611/"},{"@id":"https://doi.org/10.3390/ijms22158237","@type":"CreativeWork","about":{"@id":"https://thehippiescientist.net/herbs/nelumbo-nucifera/#entity"},"additionalProperty":[{"@type":"PropertyValue","propertyID":"study type","value":"other"}],"author":{"@type":"Organization","name":"Yang CC et al."},"datePublished":"2021","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.3390/ijms22158237"},{"@type":"PropertyValue","propertyID":"PMID","value":"34361003"}],"name":"Effect of Neferine on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice","publisher":{"@type":"Organization","name":"Int J Mol Sci"},"url":"https://pubmed.ncbi.nlm.nih.gov/34361003/"}]}