Herb Profile
Stephania Tetrandra
Botanical profile with evidence, safety, and practical fit.
Last reviewed: •3 human studies cited
C PreliminarySafety Summary: Use extra caution — Generally well tolerated for most users.
Monograph visual
Stephania Tetrandra
Generated profile category visual
Key Findings
Primary reported uses
- Anti Inflammatory
- Diuretic
- Immune Modulation
- Inflammatory signaling
Preliminary
Continue reading
- If you want to browse more herbs → All herbs
Quick Stats
Evidence level
Limited Human Evidence
Typical onset
Varies by prep
Safety rating
Use extra caution: High caution
Best for
Anti Inflammatory, Diuretic, Immune Modulation
Avoid / review if
Pregnancy/Breastfeeding Without Clinician Supervision, Known Allergy To The Plant/Family, Potential Interaction Concern With Immunosuppressants
Safety & Cautions
Generally well tolerated for most users.
28%
High caution — review carefully
Detailed safety fields
Medication interactions
- - Potential Interaction Concern With Immunosuppressants
- - Use Clinician Review For High Dose Extracts Or Chronic Use.
Pregnancy, breastfeeding, and contraindications
- - Pregnancy/Breastfeeding Without Clinician Supervision
- - Known Allergy To The Plant/Family
Safety classifications
- - Interaction-Aware: Medication or interaction context is explicitly noted.
- - Pregnancy/Breastfeeding Caution: Pregnancy or breastfeeding caution language is present.
Full safety note
- - Generally well tolerated for most users.
Safety labels
- - Interaction-Aware
- - Pregnancy/Breastfeeding Caution
Evidence Summary
PreliminaryEvidence lens
What kind of evidence supports this profile?
Early signal that needs stronger human replication before practical claims.
PreliminaryLimited Human Evidence
Human clinical evidence
Present in source signals
Human or clinical-study language is present in the reviewed fields.
Mechanistic / preclinical
Mechanism mapped
Inflammatory Signaling Modulation | NF KB Modulation
Research maturity
Preliminary or mixed
Long Term Human Evidence May Be Limited.
Safety boundary
Safety note available
Generally well tolerated for most users.
This profile cites 3 human studies.
▶How evidence grades work
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
A
Strong
Multiple RCTs, consistent direction, adequate effect size
B
Moderate
Some RCTs or consistent observational data in humans
C
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
D
Traditional / Theoretical
Traditional use only; no controlled human trials
Clinical Study Summaries
3 cited studies informing this profile. RCTs and reviews shown first.
| Study | Type | Sample | Source |
|---|---|---|---|
Stephania tetrandra S. Moore: a promising candidate drug for treating diabetic kidney disease Wang W et al. (2025) | — | — | — |
Tetrandrine--A molecule of wide bioactivity Bhagya N et al. (2016) | — | — | — |
Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents Khadilkar A et al. (2023) | — | — | — |
Dosing & Timing
Dose guidance
Preparation specific; use standardized product label for Preparation varies by tradition and product form and require source backed dosage review before therapeutic claims.
How Stephania Tetrandra Works
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How Stephania Tetrandra Works
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & Biological Pathways
Preclinical pathways
Proposed mechanisms from in vitro and animal research; these do not confirm clinical outcomes in humans.
Inflammatory Signaling ModulationNF KB Modulation
Active Compounds
Key constituents studied in Stephania Tetrandra, with full pharmacology and safety profiles.
Condition guides
Compare & Sourcing
Compare side-by-side tradeoffs or verify active marker guidelines.
Sourcing Options
Review available sources for Stephania Tetrandra
Independent database mapping. Sourcing availability is evaluated separately from safety and clinical efficacy scores.
Affiliate Disclosure: Clicking verification or shopping links may earn this site a commission at no additional cost to you. Sourcing links are selected strictly based on quality criteria and availability, never based on commission tiers. Safety warnings and evidence ratings remain independent of sourcing.
Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Editorial Review
Reviewed against source evidence and safety constraints
Profiles are checked against primary sources, cited evidence, and contraindication language before publication. This is editorial review, not personal medical advice or a named clinician endorsement.
Evidence claims are matched to human, mechanistic, or traditional-use context.
Safety language is kept conservative when interaction or population data is incomplete.
Affiliate modules are separated from evidence ratings and caution language.
Editorial Process: We synthesize preclinical pharmacology, human clinical data, and source registry context while preserving uncertainty and avoiding commercial hype.
Read Editorial Standards →Free safety checklist
Get the Stephania Tetrandra research notes
Evidence summaries, dosing context, and safety updates for this herb — straight to your inbox.
We use your email to send the checklist and occasional evidence-first supplement updates. Unsubscribe anytime. Privacy policy.