Compound Profile
11 Keto Beta Boswellic Acid
Keto boswellic acid associated with 5 LOX related signaling and inflammatory modulation.
Last reviewed: •1 source citedReport a correctionProfile-wide ·C Limited
Use extra caution — Review medications, pregnancy status, chronic conditions, and clinician guidance before use. Details
- Evidence
- Limited evidence
- Typical onset
- Varies by prep
- Safety rating
- Use extra caution: Interaction risk
- Best for
- 5 LOX, NF κB, Leukotriene Pathways
Safety
Safety & Cautions
High caution
Caution level: High. Multiple caution categories apply, or the record uses avoid/contraindication language.
- Interaction-AwareMedication or interaction context is explicitly noted.
- Liver-SensitiveLiver-related caution language appears in the profile.
- Anticoagulant CautionBleeding or anticoagulant-adjacent caution language is present.
- Pregnancy/Breastfeeding CautionPregnancy or breastfeeding caution language is present.
- Safety evidence
- limited human evidence for whole Boswellia extract, not isolated KBA
- Who should avoid this?
- No specific evidence-backed contraindication is documented for this profile. This is not the same as established safety.
- Talk to a professional if
- you use relevant medications, you are pregnant or breastfeeding, surgery is planned or recent, you have a condition named in this safety summary.
A single-dose pharmacokinetic study in 12 healthy men reported no adverse effects, but pregnancy, breastfeeding, repeated-dose, surgery, bleeding, liver, kidney, and medication-interaction safety remain insufficient.
Evidence Summary
Profile-wide ·C LimitedEvidence lens
Read as directional context, not settled clinical proof.
LimitedLimited evidence
Human clinical evidence: Present in source signals
Mechanistic / preclinical: Mechanism mapped — Inflammatory Signaling Modulation · Immune Signaling Modulation · NF KB Modulation
Research maturity: Emerging research — main contexts: 5 LOX · NF κB · Leukotriene Pathways
Safety boundary: Safety note available — Review medications, pregnancy status, chronic conditions, and clinician guidance before use.
This profile cites 1 human study.
Evidence Strength
Confidence estimate based on the design quality and consistency of published clinical trials.
11 Keto Beta Boswellic Acid has a limited evidence rating.
General wellnessGeneral wellness
Citation density
0.5
Sources
2
Effects
4
Research recency
Mixed recency
Evidence Grade
Grade C: Limited Evidence
Evaluation of methodological rigor, population reach, and evidence alignment.
- Design Match
- Randomized controlled trial
- Risk of Bias
- Low
- Consistency
- Not assessed
Strongest recorded design is a randomized controlled trial, drawn from 1 recorded study, 1 in people.
How evidence grades work
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
- Strong
- Multiple RCTs, consistent direction, adequate effect size
- Moderate
- Some RCTs or consistent observational data in humans
- Preliminary / Mixed
- Animal or in-vitro only, or conflicting human data
- Traditional / Theoretical
- Traditional use only; no controlled human trials
Clinical Study Summaries (2)1 human evidence source · 1 human trial · Participant totals not consistently reported · Consistency not yet classifiable
Filter by study class
Showing 2 of 2 studies.
What the evidence actually shows
This table contains 2 structured sources, including 1 human evidence source; 1 is a human trial.
| Study | Design | N | Dose | Duration | Population | Outcome | Result & magnitude | Source |
|---|---|---|---|---|---|---|---|---|
PK/bioavailability confirmed; food effect increases absorption; 5-LOX/inflammation. Skarke C et al. · J Clin Pharmacol · 2012 Background | Randomized controlled trial Randomly assigns participants to interventions or controls, reducing many sources of bias when the trial is conducted well. | — | — | — | — | — | — | PubMed → |
PK/bioavailability confirmed; food effect increases absorption; 5-LOX/inflammation. Sharma S et al. · Phytomedicine · 2004 Background | Other / unclear The study design is not yet classified clearly enough to infer its place in the evidence hierarchy. | — | — | — | — | — | — | PubMed → |
How 11 Keto Beta Boswellic Acid Works
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How 11 Keto Beta Boswellic Acid Works
CompoundTarget / ReceptorMechanismEffect / Outcome
Dosing
- No standardized dose
- standardized extract or essential oil free preparation when oral use is intended
Mechanisms & biological pathways
Preclinical mechanism details from scientific profiles; these represent plausible pathways but do not guarantee clinical efficacy in humans.
- Inflammatory Signaling Modulation
- Immune Signaling Modulation
- NF KB Modulation
- Inflammatory
Botanical Context
Source botanicals and comparison guides related to 11 Keto Beta Boswellic Acid.
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Compare & Sourcing
Compare side-by-side tradeoffs or verify active marker guidelines.
Review available sources for 11 Keto Beta Boswellic Acid
Independent database mapping — evaluated separately from safety and efficacy scores.
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Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Founder & Head Researcher · Oak Ridge, TN · Last reviewed August 2026
Editorial Review
Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.
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