Compound Profile
Ginkgolide B
Terpene lactone from Ginkgo biloba affecting platelet activating factor.
Last reviewed:
B ModerateMonograph visual
Ginkgolide B
Generated profile category visual
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Quick Stats
Evidence level
Moderate evidence
Typical onset
Varies by prep
Safety rating
Use extra caution: Interaction risk
Best for
PAF Receptor, Platelet Activation, Inflammatory Signaling
Found In
Botanicals that contain Ginkgolide B, with full herb profiles.
Safety & Cautions
Safety evidence
systematic-review evidence for standardized whole Ginkgo extract, not isolated ginkgolide B
Who should avoid this?
No specific evidence-backed contraindication is documented for this profile. This is not the same as established safety.
The analyzed trials did not show higher bleeding risk; isolated-compound pregnancy, breastfeeding, surgery, seizure, liver, kidney, and medication-interaction safety remains insufficient.
Talk to a healthcare professional if: you use relevant medications, you are pregnant or breastfeeding, surgery is planned or recent, you have a condition named in this safety summary.
Evidence Summary
B ModerateEvidence lens
Useful signal, but study design, dose, and population still matter.
ModerateModerate evidence
Human clinical evidence: Present in source signals
Mechanistic / preclinical: Mechanism mapped — Anti Inflammatory Signaling · Neuroprotective Activity · Platelet Activating Factor Antagonism
Research maturity: More interpretable — main contexts: PAF Receptor · Platelet Activation · Inflammatory Signaling
Safety boundary: Safety note available — Review medications, pregnancy status, chronic conditions, and clinician guidance before use.
Evidence Strength
Confidence estimate based on the design quality and consistency of published clinical trials.
Ginkgolide B has a moderate evidence evidence rating.
General wellnessGeneral wellness
Effects
3
How evidence grades work
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
A
Strong
Multiple RCTs, consistent direction, adequate effect size
B
Moderate
Some RCTs or consistent observational data in humans
C
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
D
Traditional / Theoretical
Traditional use only; no controlled human trials
How Ginkgolide B Works
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How Ginkgolide B Works
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & Biological Pathways▼
Preclinical mechanism details from scientific profiles; these represent plausible pathways but do not guarantee clinical efficacy in humans.
Anti Inflammatory SignalingNeuroprotective ActivityPlatelet Activating Factor AntagonismVascular Function SupportInflammatory Signaling Modulation
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Compare & Sourcing
Compare side-by-side tradeoffs or verify active marker guidelines.
Review available sources for Ginkgolide B
Independent database mapping — evaluated separately from safety and efficacy scores.
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Related alternatives
Herbs for similar conditions
Tradeoffs
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Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Editorial Review
Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.
Compound profile context
How to interpret Ginkgolide B
Ginkgolide B dosage by use case, onset and duration, safety limits, and interactions for paf receptor, graded against research. Moderate Human Evidence… Use this compound profile to understand mechanism, evidence quality, and practical safety context before comparing products or building a stack. A biochemical pathway connection can be useful for discovery, but it is not the same as proven benefit in humans.
When reviewing Ginkgolide B, separate the active molecule from the product category around it. Dose form, absorption, extract standardization, medication interactions, and individual sensitivity can change the real-world risk-benefit picture.
For supplement planning, avoid combining multiple compounds with overlapping sedating, stimulating, serotonergic, blood-pressure, anticoagulant, or liver-metabolism effects unless a qualified clinician has reviewed the context.