Herb Profile
Hawthorn
It is best framed around procyanidins and flavonoids.
Last reviewed: •1 human studies cited
B ModerateSafety Summary: Standard caution — Generally well tolerated for most users.
Monograph visual
Hawthorn
Generated profile category visual
Key Findings
Primary reported uses
- Cardiovascular
Moderate
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Quick Stats
Evidence level
Moderate Human Evidence
Typical onset
Varies by prep
Safety rating
Standard caution: Low caution
Best for
Cardiovascular
Avoid / review if
Cardiac Medications
Safety & Cautions
Generally well tolerated for most users.
90%
Low caution — well tolerated
Detailed safety fields
Medication interactions
- - Cardiac Medications
Full safety note
- - Generally well tolerated for most users.
Evidence Summary
ModerateEvidence lens
What kind of evidence supports this profile?
Useful signal, but study design, dose, and population still matter.
ModerateModerate Human Evidence
Human clinical evidence
Present in source signals
Human or clinical-study language is present in the reviewed fields.
Mechanistic / preclinical
Mechanism mapped
Vascular Function Support
Research maturity
More interpretable
Long Term Human Evidence May Be Limited.
Safety boundary
Safety note available
Generally well tolerated for most users.
This profile cites 1 human study.
▶How evidence grades work
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
A
Strong
Multiple RCTs, consistent direction, adequate effect size
B
Moderate
Some RCTs or consistent observational data in humans
C
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
D
Traditional / Theoretical
Traditional use only; no controlled human trials
Clinical Study Summaries
3 cited studies informing this profile. RCTs and reviews shown first.
| Study | Type | Sample | Source |
|---|---|---|---|
Hawthorn PubMed indexed authors (2012) | — | — | — |
Hawthorn PubMed indexed authors (2006) | — | — | — |
Hawthorn Fong HH et al. (2002) | — | — | — |
Dosing & Timing
Dose guidance
160 900 mg extract
How Hawthorn Works
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How Hawthorn Works
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & Biological Pathways
Preclinical pathways
Proposed mechanisms from in vitro and animal research; these do not confirm clinical outcomes in humans.
Vascular Function Support
Active Compounds
Key constituents studied in Hawthorn, with full pharmacology and safety profiles.
Condition guides
Compare & Sourcing
Compare side-by-side tradeoffs or verify active marker guidelines.
Sourcing Options
Review available sources for Hawthorn
Independent database mapping. Sourcing availability is evaluated separately from safety and clinical efficacy scores.
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Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Editorial Review
Reviewed against source evidence and safety constraints
Profiles are checked against primary sources, cited evidence, and contraindication language before publication. This is editorial review, not personal medical advice or a named clinician endorsement.
Evidence claims are matched to human, mechanistic, or traditional-use context.
Safety language is kept conservative when interaction or population data is incomplete.
Affiliate modules are separated from evidence ratings and caution language.
Editorial Process: We synthesize preclinical pharmacology, human clinical data, and source registry context while preserving uncertainty and avoiding commercial hype.
Read Editorial Standards →Free safety checklist
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