Herb Profile

Artemisia Capillaris

Artemisia capillaris

Artemisia Capillaris (Artemisia capillaris) carries a Grade C rating — limited evidence.

Last reviewed: 3 sources citedReport a correctionProfile-wide ·C Limited

Use extra caution May affect bleeding risk or circulation. Details

Evidence
Limited Evidence
Typical onset
Varies by prep
Safety rating
High caution
Best for
Liver Protective, Digestive, Inflammatory signaling
Avoid / review if
Pregnancy/Breastfeeding Without Clinician Supervision, Known Allergy To The Plant/Family, Active Liver Disease
Artemisia Capillaris monograph visual
Generated profile category visual

At a glance

From this profile's structured data
Evidence
Grade C
Safety
May affect bleeding risk or circulation.
Profile context
liver-protective, digestive
Next steps

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Safety

Safety & Cautions

May affect bleeding risk or circulation. Use caution with anticoagulants/antiplatelets and before surgery.

High caution

Caution level: High. Multiple caution categories apply, or the record uses avoid/contraindication language.

  • Interaction-AwareMedication or interaction context is explicitly noted.
  • Liver-SensitiveLiver-related caution language appears in the profile.
  • Anticoagulant CautionBleeding or anticoagulant-adjacent caution language is present.
  • Pregnancy/Breastfeeding CautionPregnancy or breastfeeding caution language is present.
Detailed safety fields

Pregnancy, breastfeeding, and contraindications

  • Pregnancy/Breastfeeding Without Clinician Supervision
  • Known Allergy To The Plant/Family
  • Active Liver Disease
  • Bleeding Disorder Or Upcoming Surgery
  • Potential Interaction Concern With Anticoagulants/Antiplatelets
  • Immunosuppressants
  • Use Clinician Review For High Dose Extracts Or Chronic Use.

Safety classifications

  • Interaction-Aware: Medication or interaction context is explicitly noted.
  • Liver-Sensitive: Liver-related caution language appears in the profile.
  • Anticoagulant Caution: Bleeding or anticoagulant-adjacent caution language is present.
  • Pregnancy/Breastfeeding Caution: Pregnancy or breastfeeding caution language is present.

Full safety note

  • May affect bleeding risk or circulation. Use caution with anticoagulants/antiplatelets and before surgery.

Safety labels

  • Interaction-Aware
  • Liver-Sensitive
  • Anticoagulant Caution
  • Pregnancy/Breastfeeding Caution

Evidence-based safety

Caution when combined

Severity and certainty are shown separately. A high-priority caution can still be theoretical: these pairings are screened from shared contraindication mechanisms and are not automatically documented clinical interactions. Provenance identifies the source fields that produced each flag; it does not upgrade the certainty of the pairwise claim.

Evidence

Evidence Summary

Evidence lens

Read as directional context, not settled clinical proof.

LimitedLimited Evidence

Human clinical evidence: Not the primary signal

Mechanistic / preclinical: Mechanism mappedNF KB Modulation · Nrf2 Activation

Research maturity: Theoretical / mechanistic researchMechanistic or unresolved evidence is kept separate from established human outcomes.

Safety boundary: Safety note availableMay affect bleeding risk or circulation.

This profile cites 3 human studies.

Study design details
Evidence Grade

Grade C: Limited Evidence

Evaluation of methodological rigor, population reach, and evidence alignment.

Design Match
Narrative review
Risk of Bias
High
Consistency
Not assessed
Strongest recorded design is a narrative review, drawn from 2 recorded studies, none of which measured an outcome in people.
How evidence grades work

Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.

Strong
Multiple RCTs, consistent direction, adequate effect size
Moderate
Some RCTs or consistent observational data in humans
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
Traditional / Theoretical
Traditional use only; no controlled human trials
Clinical Study Summaries (3)0 human evidence sources · 0 human trials · Participant totals not consistently reported · Consistency not yet classifiable

Filter by study class

Showing 3 of 3 studies.

What the evidence actually shows

This table contains 3 structured sources, including 0 human evidence sources; 0 are human trials.

StudyDesignNDoseDurationPopulationOutcomeResult & magnitudeSource

The Role of Chinese Medicine in the Treatment of Chronic Hepatitis B

Zheng S et al. · Am J Chin Med · 2025

Background
Narrative review

Summarizes selected literature without the full prespecified search and selection methods of a systematic review.

PubMed

The Pharmacological Effects and Pharmacokinetics of Active Compounds of Artemisia capillaris

Hsueh TP et al. · Biomedicines · 2021

Background
Narrative review

Summarizes selected literature without the full prespecified search and selection methods of a systematic review.

PubMed

Exploration of the potential mechanism of aqueous extract of Artemisia capillaris for the treatment of non-alcoholic fatty liver disease based on network pharmacology and experimental verification

Liang M et al. · J Pharm Pharmacol · 2024

Background
Other / unclear

The study design is not yet classified clearly enough to infer its place in the evidence hierarchy.

PubMed

Dosing & Timing

No standardized dose
Preparation specific; use standardized product label for Preparation varies by tradition and product form and require source backed dosage review before therapeutic claims.
How Artemisia Capillaris works

Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.

Mechanism Pathway — How Artemisia Capillaris Works

How Artemisia Capillaris WorksArtemisia Capillaris acts on biological target pathways via nf kb inhibition, leading to liver protective.Artemisia CapillarisBiological TargetBiological pathwayNF KB InhibitionLiver ProtectiveObservable outcomeNrf2 ActivationParallel pathway
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & biological pathways (preclinical)
  • NF KB Modulation
  • Nrf2 Activation

Active Compounds

Key constituents studied in Artemisia Capillaris, with full pharmacology and safety profiles.

Compare related active botanicals

Explore botanicals with similar chemistry, effects, or safety considerations in the Botanical Activity Atlas.

Guides that use Artemisia Capillaris

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Compare & Sourcing

Compare side-by-side tradeoffs or verify active marker guidelines.

Safety first · Harm reduction

This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.

Learn how we evaluate confidence, safety, and intensity on the methodology page.

Editorial Review

Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.

Editorial Standards →

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