Herb Profile

Lavender

Lavandula angustifolia

Oral lavender oil preparation Silexan has stronger anxiety evidence than generic lavender/aromatherapy claims; meta analysis of 5 placebo controlled trials used 80 mg/day for 10 weeks and showed anxiolytic effects with favorable tolerability.

Last reviewed: 5 sources citedReport a correctionProfile-wide ·A Strong

Use extra caution Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations. Details

Evidence
Strong Evidence
Typical onset
Varies by prep
Safety rating
Moderate caution
Best for
Sleep, Stress
Avoid / review if
Caution With Sedatives
Lavender monograph visual
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At a glance

From this profile's structured data
Evidence
Grade A
Safety
Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations.
Profile context
sleep, stress
Next steps

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Safety

Safety & Cautions

Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations. | Do not imply any lavender product has the same evidence; do not sell essential oil ingestion advice.

Elevated caution

Caution level: Elevated. One caution category applies — read it before use.

Detailed safety fields

Pregnancy, breastfeeding, and contraindications

  • Caution With Sedatives

Full safety note

  • Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations. | Do not imply any lavender product has the same evidence; do not sell essential oil ingestion advice. | Make the page specifically distinguish Silexan/oral lavender oil from aromatherapy.

Evidence-based safety

Caution when combined

Severity and certainty are shown separately. A high-priority caution can still be theoretical: these pairings are screened from shared contraindication mechanisms and are not automatically documented clinical interactions. Provenance identifies the source fields that produced each flag; it does not upgrade the certainty of the pairwise claim.

Evidence

Evidence Summary

Evidence lens

Most useful for practical interpretation when safety context also fits.

StrongStrong Evidence

Human clinical evidence: Present in source signals

Mechanistic / preclinical: Mechanism mappedStress Response Modulation

Research maturity: Established researchLong Term Human Evidence May Be Limited.

Safety boundary: Safety note availableOral standardized lavender oil may reduce anxiety symptoms in studied adult populations.

This profile cites 5 human studies.

Study design details
Evidence Grade

Grade A: Strong Evidence

Evaluation of methodological rigor, population reach, and evidence alignment.

Design Match
Meta-analysis
Risk of Bias
Low
Consistency
Consistent
Strongest recorded design is a meta-analysis, drawn from 9 recorded studies, 8 in people. No disagreement is recorded across them.
How evidence grades work

Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.

Strong
Multiple RCTs, consistent direction, adequate effect size
Moderate
Some RCTs or consistent observational data in humans
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
Traditional / Theoretical
Traditional use only; no controlled human trials
Clinical Study Summaries (8)7 human evidence sources · 0 human trials · ~9,193 participants across 1 human evidence source with reported N · Consistency not yet classifiable

Filter by study class

Showing 8 of 8 studies.

What the evidence actually shows

This table contains 8 structured sources, including 7 human evidence sources; 0 are human trials. Across 1 human evidence source with a reported sample size, the approximate participant total is 9,193; overlapping publications may include some of the same people. Source-to-conclusion relationships are not classified in this structured set, so consistency is not yet classifiable.

Profile-wide evidence grade: see the profile grade above · Confidence: not separately assigned

What would change our conclusion?

Larger, well-controlled human trials using comparable populations, doses, preparations, and clinically meaningful outcomes could materially strengthen or weaken this conclusion. Replication in a different population or a high-quality synthesis resolving current disagreement could also materially change confidence.

StudyDesignNDoseDurationPopulationOutcomeResult & magnitudeSource

Effects of lavender on anxiety: A systematic review and meta-analysis

Donelli D et al. · Phytomedicine · 2019

Background
Meta-analysis

Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies.

n=9193PubMed

Efficacy of Silexan in patients with anxiety disorders: a meta-analysis of randomized, placebo-controlled trials

M. Dold; L. Bartova; H. Volz; E. Seifritz; H. Möller; S. Schläfke; S. Kasper · European Archives of Psychiatry and Clinical Neuroscience · 2023

Background
Meta-analysis

Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies.

PubMed

Effect of Lavender Aromatherapy on Anxiety and Fatigue in Hemodialysis Patients: A Systematic Review and Meta-Analysis

Background
Meta-analysis

Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies.

Lavender aromatherapy reduced anxiety and fatigue in hemodialysis patients in pooled analyses.PubMed

Effect of Lavender Oil on Preoperative Anxiety: Systematic Review and Meta-analysis

Background
Meta-analysis

Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies.

Lavender oil significantly reduced preoperative anxiety versus control across the pooled literature.PubMed

Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance

Yeung KS et al. · Phytother Res · 2018

Background
Systematic review

Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically.

PubMed

Anxiety-Reducing Effects of Lavender Essential Oil Inhalation: A Systematic Review

Background
Systematic review

Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically.

Ten of eleven included clinical trials reported reduced anxiety after lavender essential-oil inhalation.PubMed
Show 2 more studies

Efficacy of Lavender Essential Oil in Reducing Stress, Insomnia, and Anxiety in Pregnant Women: A Systematic Review

Background
Systematic review

Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically.

All included studies reported improvement in their measured stress, anxiety, and/or sleep outcomes.PubMed

Biological activities of lavender essential oil

Cavanagh HM et al. · Phytother Res · 2002

Background
Narrative review

Summarizes selected literature without the full prespecified search and selection methods of a systematic review.

PubMed

Dosing & Timing

Dose guidance
Silexan 80 mg/day orally for 10 weeks in meta analysis. Do not generalize to all lavender oils/teas/aromatherapy. | Proprietary oral lavender oil preparation (Silexan); separate from essential oil inhalation and topical lavender.
How Lavender works

Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.

Mechanism Pathway — How Lavender Works

How Lavender WorksLavender acts on biological target pathways via hpa axis (modulation), leading to sleep quality.LavenderBiological TargetBiological pathwayHPA AxisModulationSleep Quality ↑Onset + depth
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & biological pathways

Preclinical pathways. Proposed mechanisms from in vitro and animal research; these do not confirm clinical outcomes in humans.

  • Stress Response Modulation

Active Compounds

Key constituents studied in Lavender, with full pharmacology and safety profiles.

Compare related active botanicals

Explore botanicals with similar chemistry, effects, or safety considerations in the Botanical Activity Atlas.

Guides that use Lavender

Compare & Sourcing

Compare side-by-side tradeoffs or verify active marker guidelines.

Review available sources for Lavender

Independent database mapping — evaluated separately from safety and efficacy scores.

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Safety first · Harm reduction

This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.

Learn how we evaluate confidence, safety, and intensity on the methodology page.

Editorial Review

Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.

Editorial Standards →

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Botanical profile context

How to interpret Lavender

Lavender herb profile with evidence context, key research topics, source notes, safety context, and references presented in an evidence-first format. Use this herb profile as a starting point for evidence review, not as a recommendation to start a new supplement. Botanical products can vary by plant part, extract ratio, standardization, dose, and contaminant testing, so two labels with the same common name may not behave the same way.

When reviewing Lavender, compare the traditional-use context against the human evidence, mechanism notes, and safety cautions. Pay special attention to pregnancy, breastfeeding, liver or kidney disease, blood-pressure effects, sedation, stimulation, anticoagulant use, antidepressants, and any prescription medication overlap.

For product decisions, prefer transparent labels, named extracts, clear serving sizes, and third-party quality testing. Avoid treating a long list of possible mechanisms as proof that an herb will solve a specific condition.