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Deeper context, comparisons, and practical research paths.
Herb Profile
Lavandula angustifolia
Oral lavender oil preparation Silexan has stronger anxiety evidence than generic lavender/aromatherapy claims; meta analysis of 5 placebo controlled trials used 80 mg/day for 10 weeks and showed anxiolytic effects with favorable tolerability.
Use extra caution — Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations. Details
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Safety
Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations. | Do not imply any lavender product has the same evidence; do not sell essential oil ingestion advice.
Elevated caution
Caution level: Elevated. One caution category applies — read it before use.
Evidence-based safety
Severity and certainty are shown separately. A high-priority caution can still be theoretical: these pairings are screened from shared contraindication mechanisms and are not automatically documented clinical interactions. Provenance identifies the source fields that produced each flag; it does not upgrade the certainty of the pairwise claim.
Sedation / CNS depression
Representative pairings are shown below. Large mechanism groups are intentionally summarized to keep profiles focused and crawl-efficient.
Data provenance recorded for 68 of 68 pairings in this mechanism group.
+56 more pairings share this mechanism. Use the Safety Checker to review a specific combination.
Evidence
Most useful for practical interpretation when safety context also fits.
Human clinical evidence: Present in source signals
Mechanistic / preclinical: Mechanism mapped — Stress Response Modulation
Research maturity: Established research — Long Term Human Evidence May Be Limited.
Safety boundary: Safety note available — Oral standardized lavender oil may reduce anxiety symptoms in studied adult populations.
This profile cites 5 human studies.
Evaluation of methodological rigor, population reach, and evidence alignment.
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
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Showing 8 of 8 studies.
What the evidence actually shows
This table contains 8 structured sources, including 7 human evidence sources; 0 are human trials. Across 1 human evidence source with a reported sample size, the approximate participant total is 9,193; overlapping publications may include some of the same people. Source-to-conclusion relationships are not classified in this structured set, so consistency is not yet classifiable.
Profile-wide evidence grade: see the profile grade above · Confidence: not separately assigned
What would change our conclusion?
Larger, well-controlled human trials using comparable populations, doses, preparations, and clinically meaningful outcomes could materially strengthen or weaken this conclusion. Replication in a different population or a high-quality synthesis resolving current disagreement could also materially change confidence.
| Study | Design | N | Dose | Duration | Population | Outcome | Result & magnitude | Source |
|---|---|---|---|---|---|---|---|---|
Effects of lavender on anxiety: A systematic review and meta-analysis Donelli D et al. · Phytomedicine · 2019 Background | Meta-analysis Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies. | n=9193 | — | — | — | — | — | PubMed → |
M. Dold; L. Bartova; H. Volz; E. Seifritz; H. Möller; S. Schläfke; S. Kasper · European Archives of Psychiatry and Clinical Neuroscience · 2023 Background | Meta-analysis Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies. | — | — | — | — | — | — | PubMed → |
Background | Meta-analysis Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies. | — | — | — | — | — | Lavender aromatherapy reduced anxiety and fatigue in hemodialysis patients in pooled analyses. | PubMed → |
Effect of Lavender Oil on Preoperative Anxiety: Systematic Review and Meta-analysis Background | Meta-analysis Statistically combines results from multiple eligible studies; confidence still depends on the quality, consistency, and directness of those studies. | — | — | — | — | — | Lavender oil significantly reduced preoperative anxiety versus control across the pooled literature. | PubMed → |
Yeung KS et al. · Phytother Res · 2018 Background | Systematic review Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically. | — | — | — | — | — | — | PubMed → |
Anxiety-Reducing Effects of Lavender Essential Oil Inhalation: A Systematic Review Background | Systematic review Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically. | — | — | — | — | — | Ten of eleven included clinical trials reported reduced anxiety after lavender essential-oil inhalation. | PubMed → |
Background | Systematic review Uses a predefined method to find and evaluate relevant studies, but may or may not pool their results statistically. | — | — | — | — | — | All included studies reported improvement in their measured stress, anxiety, and/or sleep outcomes. | PubMed → |
Biological activities of lavender essential oil Cavanagh HM et al. · Phytother Res · 2002 Background | Narrative review Summarizes selected literature without the full prespecified search and selection methods of a systematic review. | — | — | — | — | — | — | PubMed → |
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How Lavender Works
Preclinical pathways. Proposed mechanisms from in vitro and animal research; these do not confirm clinical outcomes in humans.
Key constituents studied in Lavender, with full pharmacology and safety profiles.
Explore botanicals with similar chemistry, effects, or safety considerations in the Botanical Activity Atlas.
Condition guides
Compare side-by-side tradeoffs or verify active marker guidelines.
Independent database mapping — evaluated separately from safety and efficacy scores.
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Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.
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Botanical profile context
Lavender herb profile with evidence context, key research topics, source notes, safety context, and references presented in an evidence-first format. Use this herb profile as a starting point for evidence review, not as a recommendation to start a new supplement. Botanical products can vary by plant part, extract ratio, standardization, dose, and contaminant testing, so two labels with the same common name may not behave the same way.
When reviewing Lavender, compare the traditional-use context against the human evidence, mechanism notes, and safety cautions. Pay special attention to pregnancy, breastfeeding, liver or kidney disease, blood-pressure effects, sedation, stimulation, anticoagulant use, antidepressants, and any prescription medication overlap.
For product decisions, prefer transparent labels, named extracts, clear serving sizes, and third-party quality testing. Avoid treating a long list of possible mechanisms as proof that an herb will solve a specific condition.